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Cost of a Stem Cell Therapy? An Estimated $512,000

Posted: June 30, 2013 at 2:55 am


The likely costs of potential stem cell therapies
and cures receive almost no attention in the media as well as
publicly from scientists and the biotech firms.
Usually any public discussion is
obliquely framed in the context of “reimbursement,” as if
industry is owed something instead of making a business decision
about what will make a profit. Euphemisms and jargon cloak unpleasant realities such as astronomical patient costs. But what reimbursement really involves are, in fact, pricing decisions and profit margins along with
lobbying campaigns for inclusion of
therapies in normal coverage of health insurance and Medicare
And today a singular figure – $512,000
for one stem cell treatment – appeared in the Wall Street
Journal
. The story by Kosaku Narioka and Phred Dvorak dealt
with what would be the first-ever human study of a treatment that
uses reprogrammed adult stem cells.
They reported that the study received
preliminary approval on Wednesday from a key panel of the Japan
Health Ministry.
The treatment involves a form of age-related macular
degeneration, which has also been targeted by the California stem
cell agency with different approaches.
Buried deep in the Wall Street Journal
article, with little other discussion, was this sentence:

“One eventual obstacle, even if tests
go well, could be cost: (Masayuki) Yamato (of Tokyo Women's Medical
University
) says initial estimates for the treatment run around ¥50
million ($512,000) per person."

The subject of costs for potential stem
cell treatments has rattled around in the background for years
without much deep public discussion. One reason is that high costs of
treatments are controversial and can trigger emotional debate.
Another reason is that it is very early in the therapy development
process and estimates are not likely to be entirely reliable.
A few years ago, however, the California stem
cell agency commissioned a study involving costs of stem cell therapies. The UC Berkeley report said,

“The cost impact of the therapy is
likely to be high, because of a therapy’s high cost per patient,
and the potentially large number of individuals who might benefit
from the therapy. This expense would put additional stress on
the Medicare and Medicaid budgets, cause private
insurance health premiums to increase, and create an incentive for
private plans to avoid covering individuals eligible for a therapy.”

The findings did not seem to be exactly
welcomed. The agency sat on the 2009 study for seven months until it
was uncovered by the California Stem Cell Report in April 2010. Then
the agency was careful to say that the study did not reflect the view
of CIRM management or board leadership.
Their wariness of being out in front on the issue could be well-advised. The pharmaceutical industry received some unpleasant attention this spring when more than 100 influential cancer specialists from more than 15 countries publicly denounced the cost of cancer drugs that exceed more than $100,000 a year.
Nonetheless pricing is critical
to both patient accessibility and therapy development. If companies
cannot make a profit on a possible therapy, it is virtually certain
not to appear in the marketplace.
While the subject remains in the
background, it does not mean there is a lack of interest. The copy of
the Berkeley stem cell cost study that was posted online by the California
Stem Cell Report has been read 11,701 times since it was made
available in April 2010 on scribd.com.
A copy of the study can be found below.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/IObtHBtAe_E/cost-of-stem-cell-therapy-estimated.html

Bluebird and Banking: Media Pluses for California Stem Cell Agency

Posted: at 2:55 am


The California stem cell agency scored
a couple of favorable publicity points last week as the result of a
successful stock offering by an award recipient and another piece
about creation of a stem cell bank in Northern California.
The IPO by bluebird bio (the company's
preferred spelling) of Massachusetts was a big winner for the
company, raising millions of dollars more than anticipated.
The Boston Globe wrote,

“Shares of the Cambridge life
sciences company bluebird bio Inc. soared almost 60 percent on their
first day of trading (last) Wednesday, an impressive debut for a
business that endured years of stagnation and another encouraging
sign for the biotechnology industry.

“The local gene therapy company
raised $101 million in an initial public offering priced at $17 per
share, higher than the $14 to $16 estimated by investment bankers.
Bluebird shares closed at $26.91 per share on Wednesday.”

The stock continues to trade around $25
a share at the time of this writing, which is good news generally for
the biotech industry.
The company received a $9.4 million
award last fall from the $3 billion stem cell agency. The company has yet to receive any actual cash from the agency as both parties work
out final details of an agreement, a spokesman for the agency said
last week.
The stem cell agency touted the
successful IPO in a blog item by  that said,

“Bluebird Bio, one of the oldest
companies in the struggling gene therapy field, is having an
outstanding first day in the stock market today, and largely by
marrying its gene therapy technology with stem cell science. The
company’s financial milestone brings hope and excitement to both
fields.”

However, the news stories about the IPO
failed to mention the stem cell agency's involvement, which would
have been nice for the agency but was to be expected given the way
news is covered.
The story about the stem cell bank
appeared on Xconomy, an Internet news service dealing with
technology. Written by Bernadette Tansey, a former San Francisco
Chronicle
reporter, the piece dealt with the both business and science of stem cell banking. She wrote,

“One of the main goals of
California’s $3 billion stem cell research agency is to draw
companies into the state so they can vie for a share of the funding.

"With a recently funded $32 million
initiative, the California
Institute for Regenerative Medicine
(CIRM) has attracted two of
the biggest US players in stem cell banking to Novato, CA, to form
one of the largest biobanks of induced pluripotent stem cells (iPS
cells) in the world.”

The stem cell bank effort has become a
minor staple in recent news coverage of CIRM, surfacing in a number
of articles since the awards were approved. One of the reasons for that is that the project has a relatively straight-forward story line compared to many research efforts and the concept of "banking" is familiar to editors, writers and readers. 

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/6WeU6kIIs6E/bluebird-and-banking-media-pluses-for.html

Mikeal sports nutrition discussion (hydration) – Video

Posted: June 29, 2013 at 6:50 am



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Article: ROBBWOLF.COM: ‘Post Paleo’ [ Paleo diet / Food Industry / Health

Posted: at 6:50 am



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Nutrition For Swimmers:Diet for swimmers – Video

Posted: at 6:50 am



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Nutrition Made Clear I The Great Courses – Video

Posted: at 6:50 am



Nutrition Made Clear I The Great Courses
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Edmonton Dietitian – 7 Nutrition Myths – Video

Posted: at 6:50 am



Edmonton Dietitian - 7 Nutrition Myths
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Mass Nutrition – Training Techniques – Occlusion (Blood flow restriction) – Video

Posted: at 6:50 am



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Good and Bad Bodybuilding Supplements: Cellucor, Musclepharm, Optimum Nutrition, Superpump – Video

Posted: at 6:50 am



Good and Bad Bodybuilding Supplements: Cellucor, Musclepharm, Optimum Nutrition, Superpump
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Hangout in English Monica Sancio

Posted: at 6:50 am



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Dialogue Practice By Nutrition Class 2 – Video

Posted: at 6:49 am



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Dialogue Practice By Nutrition Class 6 – Video

Posted: at 6:49 am



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Frey Nutrition – Beta Alanin X2 Kapseln – Video

Posted: at 6:49 am



Frey Nutrition - Beta Alanin X2 Kapseln
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Amanda Back Training Day – Pit-Bull Nutrition

Posted: at 6:49 am



Amanda Back Training Day - Pit-Bull Nutrition Supplements Athlete
Amanda training her back. Find out how shes so lean and muscular. See more on facebook.com/pitbullns and pitbullns.com.

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High Performance Nutrition Introduces a New Product, N(R), Featuring NIAGENâ„¢ to Support Neuroprotection in Contact …

Posted: at 6:49 am


IRVINE, Calif., June 25, 2013 /PRNewswire/ --High Performance Nutrition (HPN) today announced the launch of N(R)TM, an innovative daily nutritional supplement designed to protect against axon degeneration damage or trauma sustained in the course of playing contact sports. N(R) is one of the first commercially available products to feature the ingredient NIAGENTM from ChromaDex Corporation (CDXC), an innovative natural products company that provides proprietary, science-based solutions and ingredients to the dietary supplement, food and beverage, animal health, cosmetic and pharmaceutical industries.

ChromaDex Inc. developed its breakthrough ingredient NIAGEN as the patent-protected and first and only commercially available brand of nicotinamide riboside, which is known to boost levels of NAD+ in the cells. Studies have demonstrated that increasing the production of NAD+ can protect against axon degeneration caused by mechanical or neurological injury.

Recent studies have demonstrated that the head trauma that occurs in contact sports can lead to brain damage. The prevalence of repeated blows to the head in contact sports such as football, soccer and hockey has raised the concern of scientists, public officials, athletes and parents. Sean Torbati, CEO and president of HPN, believes in the importance and responsibility of protecting the health of athletes, especially that of America's youth, from debilitating brain injuries. His company has tapped into NIAGEN as a protective measure with the introduction of N(R)TM.

"N(R) addresses the recent discovery that protection from brain injury should start off the field before it continues on thefield with barriers such as helmets," said Torbati. "About three million children younger than 14 play organized tackle footballin the United States, not to mention the millions playing competitively in high school, college and beyond,as well as the millions more engaging in other sports in which helmets are worn such as baseball, lacrosse,hockey or even horseback riding. Recent findings that athletes playing soccer are also at risk for brain injury further demonstrates the potential for N(R) to be used by athletes worldwide."

Frank Jaksch, founder and CEO of ChromaDex, states "HPN is forging into a new and innovative market with N(R) by aiming to prevent or delay axonal degeneration before trauma even occurs. Backed by scientific evidence and patented nutrition technology [US7776326], N(R) is poised to revolutionize how players of contact sports think about potentially protecting themselves in the long run."

Sean Torbati further comments, "An asset as important as the human brain deserves the most protection possible, not just when you step onto the field and put on that helmet. It's a no-brainer."

For more information, please visit http://hpnformula1.com/store/Nr/

AboutNicotinamide Riboside (NR):

Sometimes referred to as the "Miracle Molecule" or the "Hidden Vitamin," NR is found naturally in trace amounts in milk and other foods and is a more potent, no-flush version of Niacin (vitamin B3). The beneficial effects of NR in humans include increased fatty acid oxidation, mitochondrial activity, resistance to the negative consequences of high-fat diets, protection against oxidative stress, prevention of peripheral neuropathy and the blocking muscle degeneration.

Published research has shown that NR is perhaps the most potent precursor to NAD+ in the mitochondria of animals. NAD+ is arguably the most important cellular co-factor for improvement of mitochondrial performance and energy metabolism. Mitochondria also play an important part in the aging process. It is hoped that by stimulating mitochondrial function with the NR molecule, scientists may see increased longevity as well as other health improvements. Researchers worldwide continue their seminal discoveries in providing evidence for unique properties of NR in neuroprotection, sirtuin activation, protection against weight gain on high fat diets and improvement of blood glucose and insulin sensitivity.

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High Performance Nutrition Introduces a New Product, N(R), Featuring NIAGENâ„¢ to Support Neuroprotection in Contact ...

European sports nutrition sector calls for end to ‘decade-long regulatory limbo’

Posted: at 6:49 am


The European Specialist Sports Nutrition Alliance (ESSNA) says there is no need for separate sports products regulation as general food law is sufficient, ahead of a European Commission report on the matter due within two years.

ESSNA vice-chair Suzane Leser told us, sport nutrition can be adequately regulated within general food legislation provided appropriate adaptations are made.

Leser reiterated the groups position at the recent 5thInternational Fresenius Conference in Mainz,Germany, where she welcomed recent changes in specialised food laws (PARNUTS) in the European Union.

The European Parliaments vote is very encouraging, but we must recognise that the European Commissions report will have enormous implications for sports nutrition products and consumers. The next two years will be crucial.

Any delay will leave the industry and its customers in limbo and draw out what has already been a decade-long debate.

This week she answered some of our questions.

What engagement do you expect with authorities?

The European Commission will be compiling the report, but the European Food Safety Authority (EFSA) will be asked for scientific advice/opinion. The Commission will prepare a mandate for EFSA with the specific technical questions to which EFSA will need to give a response.

Before doing so, however, the Commission has indicated that it will analyse the market for sports nutrition products to see how the market has evolved in past years, what sorts of products are currently on the market, and the different consumers categories.

ESSNA will engage with this report and is already liaising with key stakeholders, including the EC. We will prepare our position papers on the mandate to EFSA and our views on the sports nutrition market across Europe.

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European sports nutrition sector calls for end to 'decade-long regulatory limbo'

East West Essentials Launches New Optimal Nutrition Superfood Formula

Posted: at 6:49 am


BEVERLY HILLS, Calif., June 28, 2013 /PRNewswire/ -- East West Essentials, a family-owned and operated line of nutritional wellness supplements and the makers of the popular Optimal Cleanse program used by celebrities including Jennifer Lopez, is proud to announce its newest pharmaceutical grade product, Optimal Nutrition.

When taken as directed, the formula enhances the body's ability to lose weight while supporting natural detoxification. Nutrient-rich and refreshing, the Optimal Nutrition vegan mix is created without preservatives, fillers or bleaching agents and should be blended, shaken or stirred.

The proprietary organic superfood and superfruit formula contains a blend of adaptogens, hemp protein and tonic herbs. A single serving of Optimal Nutrition exceeds the average American's total daily nutrition intake while the hemp protein helps to regulate the body's blood sugar levels. An "adaptogen" is an herb that increases the body's ability to adapt to stress and traditionally, these medicinal herbs have been used for adrenal restoration, to rebuild and restore the body by combating the harmful effects of stress and fatigue.

"Optimal Nutrition is a powerful formula of over 20 different organic fruits and vegetables combined with supertonic adaptogens and herbs such as Ashwagandha and American Ginseng," said East West Essentials' Founder Dr. Jeanne Wilson. "These ancient herbs help regulate the entire body system heart, digestion, lymphatic, kidney, liver and most of all, your adrenal glands. Excessive adrenal activity can cause anxiety, weight gain and insomnia, and Optimal Nutrition will help reset your hormonal balance, allowing you to feel refreshed and rejuvenated."

Blending Western medicine with the Eastern philosophy of treating the body as a whole, East West Essentials' Optimal Nutrition offers anti-aging benefits and is designed to boost energy levels, maintain ideal weight, restore immunity and regulate sleep cycles.

"My go-to health experts at East West Essentials understand the importance of treating the body as a whole," said Burning Love Actress Carly Craig. "Whether I'm preparing for a role or just spending time with my family, I rely on Optimal Nutrition to maintain my energy and optimal health."

East West Essentials has been creating nutrition programs favored by Hollywood A-Listers like Jennifer Lopez for over 15 years. The East West Essentials line includes a number of programs such as the Optimal Cleanse, Optimal Qi (Chi), 7 Foods for 7 Days, Optimal Fat Flush and more. Individual supplements include Optimal Woman, Optimal Stress Blend, Optimal Fatty Acid Blend and much more.

With only 35 calories per serving, Optimal Nutrition will be sold for $86.00 in all East West Essentials' store locations and online at http://www.eastwestessentials.com.

For more information please visit http://www.eastwestessentials.com. Like us on Facebook at http://www.facebook.com/EastWestEssentials or follow us on Twitter at http://www.twitter.com/EW_Essentials.

About East West EssentialsEast West Essentials is a family-owned and operated line of nutritional wellness supplements. East West Essentials' line treats all aspects of the body with the goal of achieving optimal health for men and women. Blending western medicine with the eastern philosophy of treating the body as a whole, East West Essentials is a balance of belief systems.

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East West Essentials Launches New Optimal Nutrition Superfood Formula

MaÅ‚gorzata MÄ…czyÅ„ska – IFBB Competitor – Polish Champion Bikini Fitness – Video

Posted: at 6:49 am



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Ocean State Fitness – Chest, Shoulders, Triceps – Video

Posted: at 6:49 am



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Martial Arts Fitness | Martial Arts Falmouth | Call : 01326 319690 – Video

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