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Rapid Nutrition Continues to Expand Flagship Wellness Brand with Support of Superstar Chef Jason Roberts – Yahoo Finance

Posted: May 25, 2021 at 1:58 am


TipRanks

Markets are beset by volatility, with unpredictable swings making recent sessions something of a roller coaster. The main indexes were falling sharply at the end of last week, but Fridays release of economic data showing strong manufacturing activity provided a boost that pared back the market losses somewhat. The recent earnings season also gave reason for optimism the S&P listed companies, collectively, reported 46% year-over-year earnings gains in Q1, compared to the 20% expected. Goldman Sachs strategist David Kostin sees the generally positive macro data providing support for equities in an uncertain market environment. The combination of global reopening, elevated consumer savings, and strong corporate operating leverage will drive sharp recoveries in both economic and earnings growth... U.S. equities will continue to appreciate, albeit at a slower pace than has characterized the past 12 months equities will remain attractive relative to cash and bonds, Kostin noted. Taking this into consideration, our attention turned to three stocks that Goldman Sachs thinks have outsized growth prospects, with the firms analysts forecasting over 100% upside potential for each. Using TipRanks database, we found out that the rest of the Street is also on board, as each boasts a Strong Buy consensus rating. Rain Therapeutics (RAIN) Well start with a newly public biopharmaceutical company Rain Therapeutics. The company is developing a tumor-agnostic treatment strategy that selects patients based on the underlying genetics rather than the histology of the disease. Rain has two drug candidates in the pipeline, RAIN-32, which is undergoing several clinical trials, and RAD52, which is still in preclinical trial. Taking a closer look at the pipeline, we find that RAIN-32, an MDM2 inhibitor called milademetan, has a Phase 3 trial for WD/DD liposarcoma scheduled to begin in the second half of this year. At the same time, a Phase 2 trial, an MDM2 basket study, is also scheduled for 2H21. Beyond the WD/DD Phase 3 and the Phase 2 Basket study, the company is also looking to initiate another Phase 2 study in intimal sarcoma by early 2022. RAD52, the companys second pipeline candidate, is a novel approach to the treatment of breast, prostate, pancreatic, and ovarian cancers. The drug is still in early research phases, but lead candidate selection for clinical studies is set to begin sometime next year. As mentioned above, Rain is a newly public company; it held its IPO in April of this year. The company put 7,352,941 shares on the American public markets, at $17 each. The IPO raised about $125 million in gross proceeds. Opening coverage of this stock for Goldman Sachs, analyst Graig Suvannavejh writes: While were optimistic on RAIN-32s prospects in LPS, the revenue opportunity appears modest, as we project peak risk-unadj./adj. sales of $612mn/$428mn (assumes 70% POS), given just c.3K in US annual incidence. That said, our enthusiasm for RAIN also rests on RAIN-32s potential beyond LPS, including in intimal sarcoma (an ultra orphan cancer), and also MDM2-amplified solid tumors, which we see as a substantial market opportunity. Across these three, we project $2.2bn/$859mn in peak yr risk unadj./adj. sales in the US/EU5, with other future indications for RAIN-32 (trials to start in 2022) and also a preclinical RAD52 program (a synthetic lethality play) representing upside potential to our forecasts. In line with his bullish stance, Suvannavejh rates RAIN a Buy, and his $56 price target implies room for a stunning 252% upside potential in the next 12 months. (To watch Suvannavejhs track record, click here) Turning now to the rest of the Street, other analysts echo Suvannavejh's sentiment. As only Buy recommendations have been published in the last three months, RAIN earns a Strong Buy analyst consensus. With the average price target clocking in at $33.75, shares could soar 112% from current levels. (See RAIN stock analysis on TipRanks) Relmada Therapeutics (RLMD) The next stock on Goldman Sachs's radar, Relmada Therapeutics, is a clinical-stage pharmaceutical firm, which focuses on issues of the central nervous system. REL-1017, the companys prime pipeline candidate, is a novel NMDA receptor channel blocker under development as a treatment for major depressive disorder. Mental health is a major segment of the pharmaceutical industry, and the antidepressant piece of the mental health pie is expected to exceed $18.5 billion by 2027. Relmada started RELIANCE I, the first pivotal trial of REL-1017, in December of last year, testing the drug as an adjunctive treatment for major depression. By this past April, two additional studies, RELIANCE II and RELIANCE-OPS were underway. All three are now ongoing, and a fourth, Phase 1, study of REL-1017 as a monotherapy is set to begin in the first half of this year. Top-line data from the two pivotal studies is scheduled for release in 1H22. Goldman Sachs analyst Andrea Tan covers this stock, and she gives it a Buy rating along with a $78 price target that implies a 103% upside over the next 12 months. (To watch Tans track record, click here) We note a string of key events in 2021+ that could drive value inflection: (1) human abuse potential (HAP) study against positive control oxycodone in 2Q21 and ketamine in 2H21, where we see the market as pricing in too much risk of a negative outcome (see scenario analysis within); (2) topline data for monotherapy REL-1017 in 4Q21; and (3) topline pivotal data in adjunctive MDD (GSe peak sales of $2.5bn in 2033) in 1H22 with NDA submission to follow thereafter, all of which we are constructive on given the differentiated profile demonstrating rapid onset of action, enhanced efficacy, and good tolerability to-date, Tan opined. What does the rest of the Street have to say? 3 Buys and no Holds or Sells add up to a Strong Buy consensus rating. Given the $67.67 average price target, shares could climb 76% in the year ahead. (See RLMD stock analysis at TipRanks) Agiliti (AGTI) Well close out our look at high-potential Goldman picks with Agiliti. The company is a provider of medical equipment, offering hospitals and health systems a range of bariatrics, beds, therapy mattresses, fall prevention devices, ventilators, breast pumps, patient monitors, medical-grade adjustable chairs, and surgical equipment along with the technical support, clinical engineering, and on-site management to properly use, maintain, and adjust the myriad devices. By the numbers, Agiliti boasts over 90 service centers across the lower 48 states, supporting more than 800,000 pieces of medical equipment in over 7,000 acute care hospitals and alternate medical sites. On April 23 of this year, Agility debuted its stock on the NYSE in an IPO that was initially priced at $14. The company put over 26.3 million shares on the market, and raised approximately $431.5 million in gross proceeds in the first day of the IPO. Last week, Agiliti released its first quarterly financial report as a public company. The top line revenue, at $235 million, was 31% higher than the year-ago Q1. Net income was $9.6 million, up a strong $22.2 million from last years Q1 net loss, and EPS was 9 cents per share. Looking at the companys forward path, Goldman Sachs analyst Amit Hazan noted, While not reflected in the 1Q close balance sheet, management provided visibility to post-IPO leverage of approximately 3.3x on a pro-forma basis. While somewhat constrained from a managerial standpoint given demands from Northfield, management expects both the financial and managerial flexibility to pursue opportunistic M&A by later this year. Hazan summed up, "We view AGTIs end-to-end service model as differentiated and ideally suited in todays Hospital operating environment; we see current valuation as an attractive entry point... To this end, Hazan gives AGTI shares a Buy rating, and his $43 price target implies a 151% upside for the coming year. (To watch Hazans track record, click here) In its first few weeks on the public markets, AGTI shares have picked up 9 reviews, which include 8 Buys and just 1 Hold. The stock is selling for $17.12 and the $21.39 average price target suggests it has room for ~25% one-year upside potential. (See AGTI stock analysis on TipRanks) To find good ideas for stocks trading at attractive valuations, visit TipRanks Best Stocks to Buy, a newly launched tool that unites all of TipRanks equity insights. Disclaimer: The opinions expressed in this article are solely those of the featured analysts. The content is intended to be used for informational purposes only. It is very important to do your own analysis before making any investment.

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Rapid Nutrition Continues to Expand Flagship Wellness Brand with Support of Superstar Chef Jason Roberts - Yahoo Finance

Nutrition and Health Concerns for the Transgender Community – menshealth.com

Posted: at 1:58 am


When I began my transition in 2019, I was frustrated with the limited research and information on proper nutrition and psychological wellness. My own medical practitioners, while completely knowledgeable and supportive, could not begin to address nutrition.

When I started to do my own research, I could count on one hand the number of scientific studies or related scientific literature that dealt with nutrition for the trans community.

And good nutrition is critical for the trans community.

Whitney Linsenmeyer Ph.D., R.D., spokesperson for the Academy of Nutrition and Dietetics and Assistant Professor of Nutrition at Saint Louis University says this: "Those receiving masculinizing or feminizing hormone therapy (HT) may experience change in body weight, body composition, bone health, and cholesterol levels, among others. Nutrition can play a role in all of these factors."

Men's Health

The transitioning process can require an all-encompassing physical and mental change. Everyone's transitioning process is different, and not everyone decides to do hormone therapy, but for those that do, that can entail additional challenges.

For just one example, hormone therapy can result in modest weight gain, according to a 2020 study, but a few study participants reported a 40-pound weight gain during transitioning. These types of vast changes warrant specific dietary needs, as the body is working to adapt.

Vanessa Rissetto, M.S., R.D., C.D.N., Dietetic Internship Director of NYU, and cofounder of Culina Health echoes this: "The fact that for the LGBTQ population we have no studies to date on how their hormone treatment affects their nutritional needs is a big issue. We have no markers and I dont see any studies being funded at the moment."

Why? Linsenmeyer says that, "specific to registered dietitians, the reality is that training on nutrition care for the transgender population is rarely included in our formal education."

Without an emphasis in education, may registered dietitians may be "blind" to the nutritional needs of those in transition. And then there are other confounding factors, says Linsenmeyer.

There's breaching the fine line of cultural privacy, and researchers may feel as if they're being too intrusive by studying the topic. There's the potential for political pressure that may be indirectly applied to those involved in scientific research. Whatever the reason, the idea that an entire population group has no secure space to turn to for guidance is alarming.

As someone with a history of disordered eating, manifesting itself by way of orthorexia and body dysmorphia, I can attest to the damage poor nutrition has on ones health.

Since transitioning, and finding a new love for the body I exist in, I recognize that food and self-worth are two components that are irreplaceable in the transitioning process. When I was very sick, weighing around 100 pounds (Im around 56), my body stopped producing hormones of any kind.

I have come a long way and am currently at a healthy weight for my height. However, I am presently facing the health-related consequences of my past, including osteoporosis beginning at the age of 25 (I am now 30, and have a limited ability to increase my bone density at this stage of life), kidney and liver damage, anemia, infertility, and several others.

There are instances when Im simply scared, because my symptoms are not overt, and I can only go by what I feel to a certain extent. At this moment in time, I can only move forward by being as proactive as possible to prevent additional damage.

Any minority group, feeling outcast, would find it a greater task to advocate for themselves. I found that as a transman, this caused me to turn inward, striking an accusatory tone in my own self-talk. I have heard similar stories from others within the LGBTQ community.

This process led me to decide I was not worth it, removing all components of pleasure from my existence, including food.

Food is a way to connect with ourselves and others, it is a personal experience that is directly tied to emotions and physical wellbeing. Food contributes to our memory, concentration, mood and can alleviate additional emotion-related behavioral patterns, such as anxiety and depression.

This is through several key factors of dietary intake, including variety, adequacy, nutrient-density, and balance. By maintaining these practices in a flexible way, my body is able to perform at its best, producing the hormones and cellular energy required to stabilize mood, blood sugar, fluid balance and additional cognitive processes and emotions.

Moving forward, we must address the needs of the transgender community. "As educators we have to create a safe space for those minority groups to feel comfortable reaching our and expressing their concerns. We have to acknowledge not enough is being done, and we have to take steps toward change." says Rissetto. "We cant just sit around and point fingers, and we also cant say, well Ive done all I can."

I couldnt agree more with her sentiments. Its not a conversation about who should be doing what, its a discussion as to what can we do now to help.

Linsemeyer agrees: "My research and clinical practice centers on nutrition care for the transgender population, but the reality is that I am cisgender and will have a different perspective than a transgender or non-binary nutrition professional."

With this in mind, creating an educational program that connects cisgender and transgender professionals would be a great start. Establishing a specific nutritional organization that accounts for LGBTQ needs within their practice and realm of scope would be even better.

This needs to be more than a conversation.

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Nutrition and Health Concerns for the Transgender Community - menshealth.com

DPHHS and OPI will issue P-EBT Nutrition Assistance for Montana families – KRTV Great Falls News

Posted: at 1:58 am


GREAT FALLS The Department of Public Health & Human Services (DPHHS) will issue Pandemic Electronic Transfer (P-EBT) benefits to eligible families whose children lost access to free or reduced priced meals from October 2020 to the end of this school year as a result of the COVID-19 public health emergency. DPHHS estimates this issuance will benefit approximately 15,000 children.

School districts will submit each students monthly learning modes, such as fully virtual, fully in-person, or hybrid schedule from October 2020 through the end of the school year.

DPHHS plans to issue the first of two incremental payments to eligible families for October through February during the week of May 17.

Its estimated that monthly benefit amounts for this allocation will range from monthly amounts of $68 to $116.

A second payment to families will be made in June that will cover March through the end of the school year. Benefit amounts for this allocation have not yet been determined.

Payments will be made to families through the states Supplemental Nutrition Assistance Program (SNAP) EBT card system to current SNAP households and non-SNAP households with eligible children.

All eligible families will be issued a new EBT card specifically for the P-EBT program regardless of if they already receive SNAP. Eligible families in June will receive additional P-EBT benefits on this same card. The benefits can be used at any location that accepts SNAP/EBT cards.

DPHHS Director Adam Meier said the federal government has recently approved Montanas plan to continue the temporary assistance program. DPHHS first issued P-EBT benefits in 2020. During the week of May 17, eligible families will receive a notice from DPHHS about the P-EBT program, and within a few days of the notice the household will receive a P-EBT card.

Families do not need to apply for this benefit as DPHHS will use monthly attendance information provided by schools to determine children eligible for the program.

Montana families have faced numerous challenges over the past year, Meier said. This has been a very successful program, and were pleased to partner with OPI once again to provide this assistance.

The Office of Public Instructions (OPI) School Nutrition staff is working with DPHHS to connect eligible families to the program. Our schools and families have done an incredible job adjusting to the twists and turns thrown their way as a result of the pandemic, and this partnership will help them focus on the well-being of our children, said Superintendent of Public Instruction Elsie Arntzen. OPI will work diligently with DPHHS to ensure that this program is implemented in an efficient and transparent manner.

Children are eligible if they would have received free or reduced price meals if not for the various educational modes implemented over the past school year. Eligibility for P-EBT benefits will be determined on a monthly basis back to October, and are based on the school and childs circumstance for that particular month. To be eligible, a childs school must participate in the National School Lunch Program (NSLP).

The P-EBT program is funded by the U.S. Department of Agriculture. The federal funding for the current 2020-21 school year P-EBT issuance is not funded through the American Rescue Plan Act (ARPA). However, additional P-EBT funding was made available to states for the upcoming summer by ARPA. During the first payment issuance in 2020, a total of $21 million was issued to benefit over 64,000 Montana children for lost school days during the 2019-20 school year.

People with questions can call 1-888-706-1535, email hhshcsdpebt@mt.gov., or visit MontanaMeals.org.

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DPHHS and OPI will issue P-EBT Nutrition Assistance for Montana families - KRTV Great Falls News

Is there a link between nutrition and skin ageing? – The Statesman

Posted: at 1:58 am


There is a whole gamut of skincare products available right now online and in stores that might give our skin the glow, shine, anti-ageing, smoothness that we all crave. But, what happens when we stop using these products? Many of us have an endless list of skin concerns like pigmentation, others about dryness or oiliness, or pimples, or allergies. However, as you grow older, one of the best ways to take care of your skin is to focus on what you eat, rather than what you apply.

Many of us face challenges in deciding what to eat to keep our skin young and healthy, defining a healthy diet, and understanding the role of diet in ageing. Currently, the buzzing topic is finding ways to maintain healthy skin and delay skin aging.

According to a study, there is a close association between sugar and some food processing methods (such as grilling, frying, baking, etc) with skin ageing, and their mechanisms are related to skin advanced glycation end products. Skin health is closely linked to nutrition, which is required for all biological processes in the skin, from youth to ageing or disease. Nutritional deficiencies and eating habits can both repair and cause damage to the skin.

There are several simple things we dont follow regularly that can cause skin ageing: Not drinking enough water, deficiency of vitamin, proteins, trace elements like zinc, copper, iron, iodine, etc.

Water deficiency in the body can lead to tissue dehydration and functional issues (such as ageing and inflammation). Skin is no exception, and the state of moisture in the body is reflected in the appearance of the skin on the lips and limbs. It is advisable to at least drink more than two litres of water every day.

Almonds are a source of 15 nutrients such as vitamin E, magnesium, protein, copper, zinc, iodine, etc. A new research suggests that there may be more than one reason to add almonds to your daily skin care routine. The study found that eating almonds daily in place of typical calorie-matched snacks improved measures of both wrinkle severity and skin pigmentation in postmenopausal women. Almonds are known to be a rich source of antioxidant vitamin E and deliver essential fatty acids and polyphenols, which make them a great addition to ones daily diet for improved skin health.

Lack of Vitamin C can also cause skin disorders. They are available in abundance in oranges, lemons, strawberries and guavas.

All of the bodys tissue cells are constantly renewed, and only a sufficient protein intake can keep normal tissue renewal and repair going. The skin is no exception, with a 28-day skin renewal cycle being the norm. Apart from almonds that are rich in protein, you could also consume other protein-rich foods such as yoghurt (dahi), lentils and oats for healthier skin.

(The author is Geetika Mittal, Medical Director and Cosmetologist)

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Is there a link between nutrition and skin ageing? - The Statesman

Hot Lemon Water Before Bed: Benefits, Risks, and Nutrition – Greatist

Posted: at 1:58 am


Hot lemon water might be your citric savior.

So should you drink hot lemon water before bed?

Does hot lemon water do the damn thing? Consider the following *potential* pros and cons:

Pros

Cons

For years, weve been listening to self-proclaimed health fanatics talk about their masochistic habits. Sh*t like fasting, juice cleanses, and adding weird tiny seeds and supplements to all of your smoothies healthy for some, sure, but reserved for the truly hardcore.

While these habits may seem too extreme to the average bear looking to adopt a healthier lifestyle, theres something to be said for the more moderate, easily adaptable fixes that healthy, active people employ to maintain their status quo. And theres no better place to start than water.

Adding more water to your diet is the most basic and accessible change you can make in your day-to-day routine. Even if youre one of those I dont like the taste of water types, the best thing about water besides it being free and widely available is that you can infuse it with yummy fruits to spice things up.

This is where the almighty lemon comes in. Water with lemon is a cult classic, but recent variations like hot lemon water have been put on blast as a better choice, particularly at night.

When life gives you lemons, squeeze them into water and drink them at night.

In a 2015 paper, scientists described citrus fruits, specifically lemons, as a treasure trove for health benefits, highlighting the following health effects:

(The study may not have used these exact words, but were really cool, so there.)

For good measure, citrus fruits, like the humble lemon, are packed to the pith with organic compounds like flavonoids and alkaloids, which can offer sublime wellness bonuses (grooooooan).

Lemon water could help tackle painful kidney stones that form from mineral buildup. Typical kidney stones form from calcium oxalate and docs treat them with citrate. Guess what contains lots of citrates? Yep. Citrus fruits, like lemon, can up the levels of citrate in your pee, which helps your bod counter kidney stones.

Plus, drinking more water also helps. (Although, lets be real, very few things are going to help you when that stone passes through your pee-pee tunnel. Youll likely need to be in hospital for that. Because hurts so frickin much.)

Lemon water can work its magic no matter the time of day. However, when you glug or sip it at night before bed, lemons can work overtime, enhancing the positive outcomes. Why? Because theyre acting on a body at rest and therefore not competing for airtime in your system.

Besides the slew of beneficial effects, lemons are also one of the best sources of vitamin C. While its no secret that vitamin C helps support the immune system, research shows that vitamin C may also act alongside conventional treatments to reduce stress, depression, and anxiety.

By adding some fresh lemon juice to hot water and sipping it before bed, you may well feel the stress lift from your shoulders and reap benefits like a turbo-powered immune system, and healthier skin and hair.

While hot lemon water before bed can offer many benefits, there may be some inadvertent drawbacks to the elixir.

In a 2020 study, researchers discovered just how acidic lemons really are. Containing over five types of acid, it would be an understatement to say that lemons pack a punch. In this case, youre getting punched in the teeth, gut, and bladder. Its like kissing the alien from Alien.

The high levels of acid in lemons can harm tooth enamel. If youre drinking lemon juice right before bed, make sure you brush your teeth afterward to protect the enamel from harmful acids. (Although that combo of lemon flavor and minty toothpaste blech.)

Speaking of acid, consuming high levels of acidic juice and lying in bed could be a one-way ticket to Heartburn City. If youre prone to heartburn and indigestion, you might wanna switch drinking hot lemon water to your morning routine instead.

And then theres the matter of your bladder. It goes without saying that drinking anything and going right to bed will most likely have you waking up in the night to pee.

While theres some debate over the lemons diuretic properties (theres no research to support lemon as a diuretic), hot lemon water is still water. Knocking back lemon juice before bedtime may increase your need to pee, which gets between you and your good pal Sleep.

For those of you who are worried about your teeth, are prone to heartburn, and hate waking up at night to go to the bathroom, drinking hot lemon water before bed may not be your bag. Its more lemoff than lemon.

Lemons may seem like the star of the show here, but lets not forget that none of this happens without water.

Its well-known that increasing your water intake, in general, can lead to its own plethora of benefits. But does timing affect its health benefits?

Well, evidence on a best time to drink water is pretty limited, according to a 2019 review. There are different strategies as to when you should drink water. For example:

Supposedly, drinking water at the right time can help you alleviate stomach pain, the urge to eat too much, tiredness, and possibly even heart attack and stroke. Buuuuuut lets be real theres not a lot of science backing the existence of a right time to drink water.

So just get as much H2O as you can, when you can, and if youre prone to nighttime pee urges, avoid it before you go to bed.

The most important thing to remember in all this is to stay hydrated. The 20202025 Dietary Guidelines dont recommend a specific amount of water to drink every day (the amount of water you need in chilly Alaska isnt going to be the same as youd need in midsummer Houston, for example). But theres no upper limit so drink as much as you can.

The guidelines do recommend plain over flavored water, though. So while lemon water might be fine to drink before bed for some people, dont make every single glass a hit of citric loveliness.

Staying well-hydrated may reward you with radiant skin, healthy weight management, and a robust immune system.

Well, lemons and water, duh.

The precise goodies youll get from your lemon water depend on how strong you make it and the type of lemon you use. Yep, there are different kinds!

Heres what you can expect to find in the juice of one 48-gram (g) squeezed lemon.

Whichever type you choose, lemons are packed with vitamin C. You need around 90 mg each day, meaning that each of these little yellow fruits provides about 21 percent of your daily requirements.

Overall, lemons dont pack a whole bunch of many other nutrients. You wont find much in the way of protein or fat. The carbs are mainly fiber and sugars like glucose and fructose and the juice really doesnt provide much fiber.

Although it seems like lemon hasnt got a lot going on nutrition-wise, lemon water is a low calorie, low sugar boost to your hydration and vitamin C intake.

Hot lemon water is healthy and packs a vitamin C punch. Besides, drinking water in all its guises (except toilet water) is a good idea.

Will chugging hot lemon water before bed help you shed pounds and turn around your life? Hmm. Not sure on that one.

But it wont do you any harm. That is, unless youve got sensitive teeth, heartburn, and you loathe nocturnal visits to the privy. If youre interested in staying hydrated and getting in your daily dose of vitamin C, then lemon water is simply the zest.

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Hot Lemon Water Before Bed: Benefits, Risks, and Nutrition - Greatist

Energy and Nutrition Bars Market Size, Share, Leading Players and Analysis up to 2026 | Kellogg Co., General Mills Inc., Clif Bar & Company The…

Posted: at 1:58 am


The Energy and Nutrition Bars Market business report gives holistic view of the market and allows benchmarking all the companies in the industry, not just the ones that are focused. The research report is a significant repository for customers that contain the latest market intelligence which supports the strategic investment decisions. This business report includes both qualitative and quantitative aspects of the industry in each region and country mentioned in the market research study.

The attention on the overwhelming playersKellogg Co., General Mills Inc., Clif Bar & Company, Health Warrior Inc, Mars Incorporated, Verb Energy, Inc., NELLSON LLC, Novacap, Bite Snacks, PREMIER NUTRITION CORPORATION, yourbarfactory, SternLife, Numix, Fullwell Mill Limited, Brighter Foods, Built Bar, Aurora Intelligent Nutrition, Glanbia Plc, Nutrition & Sant SAS among others.

>>>>Get Access to Report Sample:https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-energy-and-nutrition-bars-market&SB

Energy bars are the additional bars containing both cereals and high-energy food. The energy bars are useful in offering fast energy as they provide an individual with adequate nutrition. These bars are often strengthened with minerals and vitamins that eventually assist meet dietary gaps. Due to its advantages in fast nutrition among individuals, several companies are involved to provide these bars fulfilled with nutrition.

This report also covers the impact of COVID-19 on the global market. The pandemic caused by Coronavirus (COVID-19) has affected every aspect of life globally, including the business sector. This has brought along several changes in market conditions.

Performs Competitive Analysis:The Energy and Nutrition Bars Market report incorporates the detailed analysis of the leading organizations and their thought process and what are the methodologies they are adopting to maintain their brand image in this market. The report aides the Food Fibers bees to understand the level of competition that they need to fight for to strengthen their roots in this competitive market.

Highlights following MARKET DRIVERS AND RESTRAINT:

Market Restraints:

Have any special requirement on Energy and Nutrition Bars Market report? Ask to our Industry Expert @https://www.databridgemarketresearch.com/speak-to-analyst/?dbmr=global-energy-and-nutrition-bars-market&SB

How Does This Market Insights Help?

Conducts Overall ENERGY AND NUTRITION BARS Market Segmentation:This knowledgeable market research report offers lucrative opportunities by breaking down complex market data into segments on the basis of

By Type (Energy Bars, Nutrition Bars),

Form (Organic, Conventional), Flavors (Fruit Flavor, Chocolate Flavor, Nut Flavor, Mixed Flavors),

Distribution Channel (Supermarkets/Hypermarkets, Convenience Stores, Specialist Retailers, Online Retail, Others),

Packaging (Wrappers, Boxes)

The ENERGY AND NUTRITION BARS report covers market shares for global,Europe, North America, Asia Pacific and South America.The analysis of this report has been used to examine various segments that are relied upon to witness the quickest development based on the estimated forecast frame.

Key Developments in the Market:

Purposes Behind Buying Energy and Nutrition Bars Report:-

Key questions answered in this comprehensive study Global Energy and Nutrition Bars Size, Status and Forecast 2026

What will the market size be in 2026 and what will the growth rate be?

What are the key market trends?

What is driving Global Energy and Nutrition Bars ?

What are the challenges to market growth?

Who are the key vendors in Global Energy and Nutrition Bars space?

What are the key market trends impacting the growth of the Global Energy and Nutrition Bars ?

What are the key outcomes of the five forces analysis of the Global Energy and Nutrition Bars ?

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Energy and Nutrition Bars Market Size, Share, Leading Players and Analysis up to 2026 | Kellogg Co., General Mills Inc., Clif Bar & Company The...

Shirataki noodles: 6 health benefits, nutrition facts, and meals – Medical News Today

Posted: at 1:58 am


Shirataki noodles are long, white noodles that consist of a type of starch known as glucomannan. The body does not digest this starch, making shirataki noodles very low in calories and carbohydrates.

Shirataki noodles are a popular part of Japanese cuisine. However, because of their nutritional properties and versatility, they have gained popularity in other parts of the world, particularly among those who follow low carbohydrate diets.

In this article, we will explore what shirataki noodles are in more detail, as well as their potential health benefits, how to cook them, and how to include them in meals.

Shirataki noodles consist of water and starch from the roots of the konjac plant, which is a type of yam. Other names for these noodles include konjac noodles or miracle noodles.

Manufacturers make shirataki noodles by extracting starch from konjac roots. They then use this starch to create a block, known as konnyaku.

People can eat konnyaku on its own as a meat substitute, or use it to create different shapes. Konjac starch is gelatinous and clings to itself, which makes it ideal for forming into noodles.

Shirataki noodles are unique because of the starch they contain: glucomannan. In the digestive system, glucomannan acts like a dietary fiber, which means the body does not break it down to use as energy.

This makes shirataki noodles extremely low in calories and carbohydrates, as they provide little energy.

Shirataki noodles may have a number of health benefits, depending on the individual. They include:

People may find shirataki noodles both useful and beneficial for their health if they have a food allergy, food intolerance, or a digestive condition that limits their diet.

This is because shirataki noodles are free from substances that can cause symptoms in some people. For example, they do not contain:

Some brands of shirataki noodle are also low FODMAP.

This could help people with conditions that require these dietary restrictions to eat a more varied diet while also avoiding symptoms. Shirataki noodles can act as a replacement for popular foods such as pasta, wheat noodles, and egg noodles.

Shirataki noodles may help people reach a moderate weight by providing a low calorie, low carbohydrate replacement for other starchy foods.

Additionally, there is some evidence that glucomannan may help to promote weight loss. A 2020 systematic review and meta-analysis in Obesity Medicine found an association between glucomannan supplementation and weight loss in people with overweight and obesity.

Glucomannan is also a type of soluble fiber, which is generally beneficial for weight loss as it can increase feelings of fullness.

Shirataki noodles have a low glycemic index, which means they do not cause a spike in blood sugar levels after eating them. This can make them a useful food for those with prediabetes, metabolic syndrome, or type 2 diabetes, who may need to restrict their carbohydrate intake.

However, these noodles may have additional health benefits for people with these conditions. According to a 2015 study, konjac glucomannan:

A double-blind, randomized controlled trial from 2017 found that participants who ate 400 grams (g) of glucomannan noodles for 4 weeks, followed by 4 weeks of a placebo, had:

This may make shirataki noodles a potential addition to the diet for those who are using dietary changes to reduce their risk of type 2 diabetes.

Glucomannan fiber may help to lower cholesterol by prompting the liver to release cholesterol-containing bile, which the body eliminates via bowel movements.

A systematic review in The American Journal of Clinical Nutrition found that taking around 3 g of glucomannan fiber each day caused a 10% reduction in low-density lipoprotein (LDL) cholesterol.

This research focuses on glucomannan specifically, rather than shirataki noodles. As such, people should not rely on this food to treat high cholesterol.

The glucomannan fiber in shirataki may act as a prebiotic. Prebiotics are substances that feed beneficial bacteria in the large intestine.

A critical review in the International Journal of Biological Macromolecules notes that glucomannan does not break down in the stomach, so it can be a source of food for gut flora.

Scientists are only beginning to understand the ways in which gut bacteria affect human health. However, they are essential for digestion and nutrient absorption. Gut bacteria may also influence other aspects of health, such as mood and body weight.

As with other sources of soluble fiber, shirataki noodles can help aid digestion and promote regular bowel movements. This may help people who experience constipation or who want to increase their fiber intake to generally improve digestion.

Shirataki noodles mainly consist of water and fiber. As a result, they contain few essential nutrients.

A 112 g serving of shirataki noodles contains:

The noodles also contain about 20.2 mg of calcium per serving.

Some companies may add other ingredients to improve markers, such as texture or flavor. Keep in mind that this may change the nutritional value of the noodles.

Shirataki noodles are generally well-tolerated. However, a 2014 study notes that glucomannan supplementation can cause side effects, such as bloating, trapped gas, or diarrhea.

It is possible that eating large amounts of shirataki noodles may cause similar side effects, though no research exists on how common this is.

Additionally, while shirataki noodles are low in calories and carbohydrates, they contain very little energy and almost no vitamins or minerals.

As such, it is important to eat them as part of a balanced diet that also contains plenty of nutrient-dense foods. Otherwise, a person may develop deficiencies.

Shirataki noodles are very low in carbohydrates. For this reason, people following the ketogenic diet can eat them.

People following the keto diet should try to mix shirataki noodles with other carbohydrate replacement foods, such as cauliflower, zucchini, or spaghetti squash. People can also use these foods as substitutes for rice, pasta, and noodles. Unlike shirataki, though, they have more nutritional value.

Learn more about the potential benefits and risks of the keto diet.

Shirataki noodles often come bagged in water. To prepare them:

At this point, some people prefer to cook the noodles again in a hot, dry frying pan. This evaporates any remaining water and can improve the texture or flavor before adding the noodles to a dish.

Shirataki noodles are versatile. People can add them to many dishes, as they absorb the flavor of other foods. People can use them in a similar way to pasta, rice, and other types of noodle.

To infuse the noodles with more flavor, cook them as normal and then add them to a sauce or broth. Allow them to simmer in the liquid for a few minutes to absorb the flavors.

Some ideas for meals using shirataki noodles include:

Shirataki noodles are fiber-rich noodles that may have some health benefits, such as helping people maintain a moderate weight and improving digestive health. They are low in calories and carbohydrates, and free from common allergens.

People can use shirataki noodles in a wide range of dishes. However, it is important not to rely on them, as they do not contain many nutrients.

Continued here:
Shirataki noodles: 6 health benefits, nutrition facts, and meals - Medical News Today

Shop Small with Stevie – Island Vybz Nutrition, The Filling Station, Valley View Farms – wmar2news.com

Posted: at 1:58 am


Each week, WMAR-2 News meteorologist Stevie Daniels highlights local small businesses during Shop Small with Stevie.

Island Vybz Nutrition in Baltimore offers delicious healthy shakes, smoothies, teas, protein waffles, and more. You can even set up one on one nutritional counseling and attend a community event!

Stop into The Filling Station for a coffee,breakfast burrito, sandwich, or snack! Window service, website ordering, and outdoor seating are available.

Valley View Farms is the perfect go-to for your summer garden. Whether you're looking for plants, flowers, decor, or even furniture, the friendly and knowledgeable staff has you covered.

If you're a small business owner who would like to be featured in an upcoming segment, email Stevie at stevie.daniels@wmar.com or reach out on Facebook and Twitter @StevieDanialsWX and on Instagram at stevie_daniels_ See more featured, LOCAL, businesses in our Shop Small with Stevie photo gallery.

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Shop Small with Stevie - Island Vybz Nutrition, The Filling Station, Valley View Farms - wmar2news.com

REDCON1, The Fastest Growing Sports Nutrition Brand Will Open It’s Second Flagship Gym In Nashville, TN – PRNewswire

Posted: at 1:58 am


Special guests at the grand opening of the REDCON1 Nashville Gyminclude Kai Greene, Dana Linn Bailey, Rob Bailey, Kenny Omega, Sage Northcutt, and former 9/11 New York City Police Commissioner Bernard Kerik.

At a staggering 50,000 square feet, this global destination will double as a world-class premium gym and as an official REDCON1 retail store.

We're also proud to announce this will be an Official NPC Certified Gym and the North American Panatta Retail Showroom. These key partnerships allow us to create a destination that's equipped to support any professional athletes yet made available to the public.

World-renowned three-time Arnold Classic champion, REDCON1 Elite Athlete, and first ISSA's Global Fitness Ambassador Kai Greene says, "The sport of bodybuilding has been my passion since a young man growing up in Brooklyn, New York. It was a privilege to have an active hands-on role in planning and designing this state-of-the-art fitness facility. We were intentionally thoughtful on each handpicked piece of equipment and free weight to ensure everyone of all skillsets or fitness goals can attain and maintain their goals."

Aaron Singerman, Founder of REDCON1, is excited to open a second brick-and-mortar location in Nashville.

"Since launching REDCON1 in 2016 the brand has nurtured a global community spanning 80+ countries. We're excited to plant our roots in the heart of Nashville and become part of the local fabric. Just as we design our healthy on-the-go supplements and vitamins for mass inclusion so will our gym. This gym will provide a destination for all people with varying goals to live a healthier lifestyle," explained Singerman.

"REDCON1's customer base is nearly 40% military, veterans, first responders, police, and paramedics. I know many law enforcement officers and first responders who rely on REDCON1's high-quality supplements to not only reach but exceed, their fitness and strength training goals. That allows our brave men and women to operate on the level we need to keep our communities safe," said Kerik, the 40th Commissioner of the New York Police Department.

ABOUT RECON1 -->

REDCON1is a mission-based company founded on a simple principle - create the highest quality supplements for people that need to get the most out of their workout and workday. REDCON1 offers nutritional supplements and apparel that appeal to everyone from beginners to serious athletes. Its strong military branding is highlighted by more than 24,000 Tier Operators around the world, many of which are currently serving with or are retired from the United States Armed Forces. The products feature effective formulas that deliver real results while building a brand that stands for transparency, hard work, honesty, and integrity. Additionally, the Company has significant community engagement through REDCON1 Foundation, the primary goal of which is making a positive impact on families of the United States military heroes. For additional information, visit redcon1.com, watch the brand story, and redcon1foundation.com.

CONTACTRyan MonahanREDCON1, Chief Marketing Officer[emailprotected]

SOURCE REDCON1

https://redcon1.com/

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REDCON1, The Fastest Growing Sports Nutrition Brand Will Open It's Second Flagship Gym In Nashville, TN - PRNewswire

ACTED responds to the deteriorating nutritional situation in the North of DRC – Democratic Republic of the Congo – ReliefWeb

Posted: at 1:58 am


In the North of the Democratic Republic of Congo, the nutritional situation of the host communities and refugees is of concern.

ACTED is responding to the needs of refugees and host communities with the support of the United States Agency for International Development. This project has focused on the provinces of Bas Ul, Nord Oubangui and Sud Oubangui.

According to our estimates, in the province of South Oubangui alone, nearly 406,788 people are in an emergency food insecurity crisis.

Studying the nutritional situation to better respond to it

ACTED has conducted an analysis to assess the level of food insecurity in the Democratic Republic of Congo between June 2018 and December 2019. The results of the analysis show that the three provinces are under pressure and facing serious food insecurity problems. Residents in the area struggle to meet their daily food needs.

The region also hosts a large number of refugees who have settled in the country, fleeing the conflicts in the Central African Republic. Refugees are no exception and are also in a situation of severe food insecurity.

Food aid to host communities and refugees

Since August 2019, ACTED has been implementing an immediate food assistance project for host communities but also for refugees present in the region. The project activities contribute to the improvement of the living conditions of the populations while promoting resilience.

ACTED carries out food and cash distributions to respond to urgent and immediate needs. Then, in another phase, we carry out agricultural recovery activities with trainings, seed and tool distributions to improve the production capacities of vulnerable populations.

Before each distribution, the people we accompany have attended information sessions on food management, but also on the actions to be taken against Covid-19. The women were able to attend information meetings on breastfeeding and reproductive health practices.

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ACTED responds to the deteriorating nutritional situation in the North of DRC - Democratic Republic of the Congo - ReliefWeb

Guardion Health Sciences to Acquire Activ Nutritional, LLC and Its Well-Known Viactiv Brand of Products from Adare Pharmaceuticals, Inc. – Yahoo…

Posted: at 1:58 am


TipRanks

Markets are beset by volatility, with unpredictable swings making recent sessions something of a roller coaster. The main indexes were falling sharply at the end of last week, but Fridays release of economic data showing strong manufacturing activity provided a boost that pared back the market losses somewhat. The recent earnings season also gave reason for optimism the S&P listed companies, collectively, reported 46% year-over-year earnings gains in Q1, compared to the 20% expected. Goldman Sachs strategist David Kostin sees the generally positive macro data providing support for equities in an uncertain market environment. The combination of global reopening, elevated consumer savings, and strong corporate operating leverage will drive sharp recoveries in both economic and earnings growth... U.S. equities will continue to appreciate, albeit at a slower pace than has characterized the past 12 months equities will remain attractive relative to cash and bonds, Kostin noted. Taking this into consideration, our attention turned to three stocks that Goldman Sachs thinks have outsized growth prospects, with the firms analysts forecasting over 100% upside potential for each. Using TipRanks database, we found out that the rest of the Street is also on board, as each boasts a Strong Buy consensus rating. Rain Therapeutics (RAIN) Well start with a newly public biopharmaceutical company Rain Therapeutics. The company is developing a tumor-agnostic treatment strategy that selects patients based on the underlying genetics rather than the histology of the disease. Rain has two drug candidates in the pipeline, RAIN-32, which is undergoing several clinical trials, and RAD52, which is still in preclinical trial. Taking a closer look at the pipeline, we find that RAIN-32, an MDM2 inhibitor called milademetan, has a Phase 3 trial for WD/DD liposarcoma scheduled to begin in the second half of this year. At the same time, a Phase 2 trial, an MDM2 basket study, is also scheduled for 2H21. Beyond the WD/DD Phase 3 and the Phase 2 Basket study, the company is also looking to initiate another Phase 2 study in intimal sarcoma by early 2022. RAD52, the companys second pipeline candidate, is a novel approach to the treatment of breast, prostate, pancreatic, and ovarian cancers. The drug is still in early research phases, but lead candidate selection for clinical studies is set to begin sometime next year. As mentioned above, Rain is a newly public company; it held its IPO in April of this year. The company put 7,352,941 shares on the American public markets, at $17 each. The IPO raised about $125 million in gross proceeds. Opening coverage of this stock for Goldman Sachs, analyst Graig Suvannavejh writes: While were optimistic on RAIN-32s prospects in LPS, the revenue opportunity appears modest, as we project peak risk-unadj./adj. sales of $612mn/$428mn (assumes 70% POS), given just c.3K in US annual incidence. That said, our enthusiasm for RAIN also rests on RAIN-32s potential beyond LPS, including in intimal sarcoma (an ultra orphan cancer), and also MDM2-amplified solid tumors, which we see as a substantial market opportunity. Across these three, we project $2.2bn/$859mn in peak yr risk unadj./adj. sales in the US/EU5, with other future indications for RAIN-32 (trials to start in 2022) and also a preclinical RAD52 program (a synthetic lethality play) representing upside potential to our forecasts. In line with his bullish stance, Suvannavejh rates RAIN a Buy, and his $56 price target implies room for a stunning 252% upside potential in the next 12 months. (To watch Suvannavejhs track record, click here) Turning now to the rest of the Street, other analysts echo Suvannavejh's sentiment. As only Buy recommendations have been published in the last three months, RAIN earns a Strong Buy analyst consensus. With the average price target clocking in at $33.75, shares could soar 112% from current levels. (See RAIN stock analysis on TipRanks) Relmada Therapeutics (RLMD) The next stock on Goldman Sachs's radar, Relmada Therapeutics, is a clinical-stage pharmaceutical firm, which focuses on issues of the central nervous system. REL-1017, the companys prime pipeline candidate, is a novel NMDA receptor channel blocker under development as a treatment for major depressive disorder. Mental health is a major segment of the pharmaceutical industry, and the antidepressant piece of the mental health pie is expected to exceed $18.5 billion by 2027. Relmada started RELIANCE I, the first pivotal trial of REL-1017, in December of last year, testing the drug as an adjunctive treatment for major depression. By this past April, two additional studies, RELIANCE II and RELIANCE-OPS were underway. All three are now ongoing, and a fourth, Phase 1, study of REL-1017 as a monotherapy is set to begin in the first half of this year. Top-line data from the two pivotal studies is scheduled for release in 1H22. Goldman Sachs analyst Andrea Tan covers this stock, and she gives it a Buy rating along with a $78 price target that implies a 103% upside over the next 12 months. (To watch Tans track record, click here) We note a string of key events in 2021+ that could drive value inflection: (1) human abuse potential (HAP) study against positive control oxycodone in 2Q21 and ketamine in 2H21, where we see the market as pricing in too much risk of a negative outcome (see scenario analysis within); (2) topline data for monotherapy REL-1017 in 4Q21; and (3) topline pivotal data in adjunctive MDD (GSe peak sales of $2.5bn in 2033) in 1H22 with NDA submission to follow thereafter, all of which we are constructive on given the differentiated profile demonstrating rapid onset of action, enhanced efficacy, and good tolerability to-date, Tan opined. What does the rest of the Street have to say? 3 Buys and no Holds or Sells add up to a Strong Buy consensus rating. Given the $67.67 average price target, shares could climb 76% in the year ahead. (See RLMD stock analysis at TipRanks) Agiliti (AGTI) Well close out our look at high-potential Goldman picks with Agiliti. The company is a provider of medical equipment, offering hospitals and health systems a range of bariatrics, beds, therapy mattresses, fall prevention devices, ventilators, breast pumps, patient monitors, medical-grade adjustable chairs, and surgical equipment along with the technical support, clinical engineering, and on-site management to properly use, maintain, and adjust the myriad devices. By the numbers, Agiliti boasts over 90 service centers across the lower 48 states, supporting more than 800,000 pieces of medical equipment in over 7,000 acute care hospitals and alternate medical sites. On April 23 of this year, Agility debuted its stock on the NYSE in an IPO that was initially priced at $14. The company put over 26.3 million shares on the market, and raised approximately $431.5 million in gross proceeds in the first day of the IPO. Last week, Agiliti released its first quarterly financial report as a public company. The top line revenue, at $235 million, was 31% higher than the year-ago Q1. Net income was $9.6 million, up a strong $22.2 million from last years Q1 net loss, and EPS was 9 cents per share. Looking at the companys forward path, Goldman Sachs analyst Amit Hazan noted, While not reflected in the 1Q close balance sheet, management provided visibility to post-IPO leverage of approximately 3.3x on a pro-forma basis. While somewhat constrained from a managerial standpoint given demands from Northfield, management expects both the financial and managerial flexibility to pursue opportunistic M&A by later this year. Hazan summed up, "We view AGTIs end-to-end service model as differentiated and ideally suited in todays Hospital operating environment; we see current valuation as an attractive entry point... To this end, Hazan gives AGTI shares a Buy rating, and his $43 price target implies a 151% upside for the coming year. (To watch Hazans track record, click here) In its first few weeks on the public markets, AGTI shares have picked up 9 reviews, which include 8 Buys and just 1 Hold. The stock is selling for $17.12 and the $21.39 average price target suggests it has room for ~25% one-year upside potential. (See AGTI stock analysis on TipRanks) To find good ideas for stocks trading at attractive valuations, visit TipRanks Best Stocks to Buy, a newly launched tool that unites all of TipRanks equity insights. Disclaimer: The opinions expressed in this article are solely those of the featured analysts. The content is intended to be used for informational purposes only. It is very important to do your own analysis before making any investment.

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Guardion Health Sciences to Acquire Activ Nutritional, LLC and Its Well-Known Viactiv Brand of Products from Adare Pharmaceuticals, Inc. - Yahoo...

What is Alzheimer’s Disease? Symptoms & Causes | alz.org

Posted: at 1:57 am


Alzheimer's is a type of dementia that affects memory, thinking and behavior. Symptoms eventually grow severe enough to interfere with daily tasks.

Subscribe to our e-newsletter to learn how you can help those affected by Alzheimer's.

Donate today so we can continue advancing research and providing free 24/7 support to those who depend on it.

If you or someone you know has been diagnosed with Alzheimer's or another dementia, you are not alone. The Alzheimer's Association is the trusted resource for reliable information, education, referral and support to millions of people affected by the disease.

The most common early symptom of Alzheimer's is difficulty remembering newly learned information.

Just like the rest of our bodies, our brains change as we age. Most of us eventually notice some slowed thinking and occasionalproblems with remembering certain things. However, serious memory loss, confusion and other major changes in the way our minds work may be a sign that brain cells are failing.

The most common early symptom of Alzheimer's is difficulty remembering newly learned information because Alzheimer's changes typically begin in the part of the brain that affects learning. As Alzheimer's advances through the brain it leads to increasingly severe symptoms, including disorientation, mood and behavior changes; deepening confusion about events, time and place; unfounded suspicions about family, friends and professional caregivers; more serious memory loss and behavior changes; and difficulty speaking, swallowing and walking.

People with memory loss or other possible signs of Alzheimers may find it hard to recognize they have a problem. Signs of dementia may be more obvious to family members or friends. Anyone experiencing dementia-like symptoms should see a doctor as soon as possible. If you need assistance finding a doctor with experience evaluating memory problems, your local Alzheimer's Association can help. Earlier diagnosis and intervention methods are improving dramatically, and treatment options and sources of support can improve quality of life. Two helpful support resources you can tap into are ALZConnected, our messages boards and online social networking community, and Alzheimer's Navigator, a web tool that creates customized action plans, based on answers you provide through short, online surveys.

Take our free, online education courses: Understanding Alzheimer's and Dementia and Know the 10 Signs: Early Detection Matters

Many people have trouble with memory this does NOT mean they have Alzheimer's. There are many different causes of memory loss. If you or someone you know is experiencing symptoms of dementia, it is best to visit a doctor so the cause can be determined.

Microscopic changes in the brain begin long before the first signs of memory loss.

The brain has 100 billion nerve cells (neurons). Each nerve cell connects with many others to form communication networks. Groups of nerve cells have special jobs. Some are involved in thinking, learning and remembering. Others help us see, hear and smell.

To do their work, brain cells operate like tiny factories. They receive supplies, generate energy, construct equipment and get rid of waste. Cells also process and store information and communicate with other cells. Keeping everything running requires coordination as well as large amounts of fuel and oxygen.

Scientists believe Alzheimer's disease prevents parts of a cell's factory from running well. They are not sure where the trouble starts. But just like a real factory, backups and breakdowns in one system cause problems in other areas. As damage spreads, cells lose their ability to do their jobs and, eventually die, causing irreversible changes in the brain.

Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells.

Though autopsy studies show that most people develop some plaques and tangles as they age, those with Alzheimers tend to develop far more and in a predictable pattern, beginning in the areas important for memory before spreading to other regions.

Scientists do not know exactly what role plaques and tangles play in Alzheimer's disease. Most experts believe they somehow play a critical role in blocking communication among nerve cells and disrupting processes that cells need to survive.

It's the destruction and death of nerve cells that causes memory failure, personality changes, problems carrying out daily activities and other symptoms of Alzheimer's disease.

Learn More: Take the Brain Tour

In 1906, German physician Dr. Alois Alzheimer first described "a peciliar disease" one of profound memory loss and microscopic brain changes a disease we now know as Alzheimer's.

Today, Alzheimer's is at the forefront of biomedical research. Researchers are working to uncover as many aspects of Alzheimer's disease and other dementias as possible. Some of the most remarkable progress has shed light on how Alzheimer's affects the brain. The hope is this better understanding will lead to new treatments. Many potential approaches are currently under investigation worldwide. Sign up for our weekly e-news to receive updates about Alzheimers and dementia care and research.

Learn more: Research and Progress

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What is Alzheimer's Disease? Symptoms & Causes | alz.org

Hackensack Meridian Health and Eisai Inc. Join Forces to Support the Expansion of Alzheimer’s Disease Detection and Services for Patients – Network…

Posted: at 1:57 am


May 24, 2021

Hackensack MeridianHealth,New Jerseys largest, most comprehensive and integrated health network, and Eisai Inc., the U.S. pharmaceutical subsidiary of Eisai Co., Ltd., have entered into a research collaboration agreement that initially aims to help address the significant unmet needs of people living with Alzheimers disease, especially those experiencing the earliest stages of the disease, known as Mild Cognitive Impairment.

We are proud to join forces with Eisai in our quest to expand early Alzheimers disease detection and improve community services for patients, caregivers and families impacted by the disease and other types of dementia, said Robert C. Garrett, FACHE, CEO, Hackensack MeridianHealth. Hackensack MeridianHealthsmission is to transform health care and this collaboration will help us to achieve our goals and benefit our communities.

The organizations will support the expansion of early Alzheimers disease education, detection and community services for patients and caregivers, as well as evaluate emerging tools and technological diagnostic solutions through real-world, evidence-based investigation within theHackensack MeridianHealthnetwork. The ultimate goals of this collaboration areto further enhance care plans to support patients and their caregivers in each stage of the disease and to contribute to scalable and reproducible multi-disciplinary approaches for patient identification and management in early Alzheimers disease.

The collaboration with Hackensack MeridianHealthis an exciting next step in both organizations legacy and leadership in discovering and providing solutions to people living with Alzheimers disease and other related dementias, said Alexander Scott, executive vice president, Integrity at Eisai. As part of Eisaishuman health caremission, we are dedicated to making a difference for patients and their families.

Hackensack MeridianHealthand Eisai each have unique expertise and a deep commitment to the treatment and care of Alzheimers disease patients and their caregivers. The Center for Memory Loss and Brain Health at Hackensack Meridian Hackensack University Medical Center offers integrated, high-quality screening, diagnostic and treatment services for adults living with cognitive or memory impairment caused by conditions such as Alzheimers disease and other types of dementia. It is led by Manisha Parulekar, M.D., AGSF, FACP, division chief, Geriatrics; Florian Thomas, M.D., Ph.D., chair and professor, Neurology and Neuroscience Institute; Laurie G. Jacobs, M.D., AGSF, FACP, chair and professor of Medicine; and Lisa Tank, M.D., chief medical officer, Hackensack University Medical Center, who all hold faculty appointments at Hackensack Meridian School of Medicine.

Both Hackensack MeridianHealthand Eisai share a common goal to increase community awareness about the importance of early detection, especially in the earliest stages of cognitive loss before patients meet the criteria for a dementiadiagnosis, said Dr. Parulekar. This awareness will help improve the patient and caregiver journey for those living with memory disorders.

For decades, Eisai has led the way in dementia research and development through scientific discovery, listening to patients, caregivers, and healthcare professionals, exploring solutions outside of traditional medicinal therapies, and collaboration agreements, such as the one with Hackensack MeridianHealth.

We recognize the importance of collaborating with organizations so we can effectively improve resources and services that aim to advance brain health within our community, especially among patients and their families, caregivers and the general public, added Dr. Thomas.

For more information about the research collaboration agreement between Hackensack MeridianHealthand Eisai, please contact Ashley R. Calle, communications manager, Hackensack MeridianHealthFoundation, at 201-937-2295 orashley.calle@hmhn.org, or Libby Holman, communications director, Eisai, at 201-753-1945 orlibby_holman@eisai.com.

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Hackensack Meridian Health and Eisai Inc. Join Forces to Support the Expansion of Alzheimer's Disease Detection and Services for Patients - Network...

She’s taking the fight to Alzheimer’s disease – Northwestern University NewsCenter

Posted: at 1:57 am


Weinberg second-year student Victoria Da Conceicao learned at a young age what it means to fight back against adversity.

As a child, she always lived near her grandmother outside of Oakland, Calif., until her family moved to follow work outside the Bay Area. At the age of 16, feeling homesick, she decided to return on her own and move into her grandmothers home to attend high school nearby.

But one day when they were supposed to meet after school, Da Conceicaos grandmother never came to pick her up. Her uncle found her later that day wandering in a park close to the school.

At that point forward, their lives changed forever.

By the time her grandmother was eventually diagnosed with Alzheimers disease, she was no longer able to drive or leave the house on her own. Having worked hard at many jobs since immigrating from Mexico when she was 19 years old, she was an inspiration to her granddaughter. But now shed lost her sense of purpose and the spirit of independence she was known for.

Da Conceicao began to research therapies for the disease. She learned that puzzles, essential oils and custom coloring books could help enhance mood, engage the brain and improve memory.

I still remember the evening I came up with the idea for coloring books for Alzheimers patients. My grandmother and I were eating dinner, and she was telling me all these old stories. I saw her face light up in a way I had not seen in months. She got up from the table and came back with photos of her time in Mexico, her family and her favorite places there.

She now had the makings of her own small business, which she founded in 2018 while she was still in high school. ThroughAlzheimers Brain Box, she assembles, packs and ships care packages throughout the U.S.

I knew I had to be brave for her, so I never let her see how scared I was, Da Conceicao said. Once I decided to create the company, I had an outlet for my concerns. I poured my heart into my work and over time, my fears lessened, and I found solace in refining my products.

Now a second-year student in theWeinberg College of Arts and Sciences, shes upping her game this quarter by taking the class Entrepreneurial Endurance, Leadership & Mindset through theFarley Center for Entrepreneurship and Innovationin the McCormick School of Engineering.

Im so fortunate to be at Northwestern, in this collaborative environment where people work across schools and disciplines to actually help each other, she said. In fact, Ive found several partners among my fellow students whove brought diverse skills to help make the company go.

Among her Northwestern collaborators is first-year student Jenna Ginsburg of the School of Communication, who also has a family member affected by Alzheimers. She has been handling social media and administrative duties for the company this year.

As CEO and founder of Alzheimers Brain Box, Da Conceicao has been a corporate sponsor of the Alzheimers Association Walnut Creek Chapter to help raise research funds, and she has partnered with AARP to raise awareness about the ways minorities and women are disproportionately affected by the disease.

A study by the Centers for Disease Control and Prevention finds that, among people ages 65 and older, African Americans and Hispanics have the highest prevalence of Alzheimers disease and dementia. More than six million Americans, two-thirds of whom are women, suffer from Alzheimers disease, according to theAlzheimers Association. And during the COVID-19 pandemic, deaths from Alzheimers and related dementias have increased by 16%.

Once I decided to create the company, I had an outlet for my concerns.

As the pandemic evolves to a new phase this summer, Da Conceicao plans to return to California to work with memory care facilities, hospice groups and medical centers. One such partnership is already underway with Yolo Hospice in Davis, northeast of the Bay Area.

There she has added a twist to the original package, incorporating writing prompts based on information patients loved ones provide in order to facilitate some of that same storytelling that brings her own grandmother so much joy and comfort.

Her grandmother always says, El querer es poder, which means to want is to be able.

This has stuck with me over the years, Da Conceicao said. My dream is to continue working for Alzheimers Brain Box after I graduate, but to be able to support even more senior care facilities before that. My grandmothers support provides the strength I need to pursue this dream. And I know that, no matter what happens, Ill always be able to go home to her.

If you are interested in bringing customized care to your facility, contact Victoria Da Conceicao atAlzheimers Brain Box.

Originally posted here:
She's taking the fight to Alzheimer's disease - Northwestern University NewsCenter

Mathematical Model of the Brain May Identify Gene Changes Responsible for Cognitive Decline in Aging – Pharmacy Times

Posted: at 1:57 am


A new mathematical model described in eLife suggests there are key similarities between Alzheimer disease and healthy aging. According to the study authors, this model provides insights into the multiscale biological alterations in the elderly and neurodegenerative brain, which have important implications for identifying treatment targets for Alzheimer disease.

The researchers developed this mathematical model using a wide range of biological data, including both microscopic information from gene activity and macroscopic information about the brain's burden of toxic proteins (tau and amyloid), its neuronal function, cerebrovascular flow, metabolism, and tissue structure from molecular PET and MRI scans.

In both aging and disease research, most studies incorporate brain measurements at either micro or macroscopic scale, failing to detect the direct causal relationships between several biological factors at multiple spatial resolutions, said Quadri Adewale, a PhD candidate at the Department of Neurology and Neurosurgery, McGill University, Canada, in a press release. We wanted to combine whole-brain gene activity measurements with clinical scan data in a comprehensive and personalized model, which we then validated in healthy aging and Alzheimer's disease.

The study examined 460 patients who had at least 4 different types of brain scan at 4 different time points as part of the Alzheimer Disease Neuroimaging Initiative cohort, with 151 clinically identified as asymptomatic or healthy control, 161 with early mild cognitive impairment (ECMI), 113 with late mild cognitive impairment (LCMI), and 35 with probable Alzheimer disease. The data from these multimodal scans were combined with data on gene activity from the Allen Human Brain Atlas, which provides details on whole-brain gene expression for 20,267 genes.

The researchers then split the brain into 138 different gray matter regions for the purposes of combining the gene data with the structural and functional data from the scans. They then explored causal relationships between the spatial genetic patterns and information from their scans and cross-referenced this to age-related changes in cognitive function.

According to the study, the model was most capable of predicting the extent of decline in cognitive function for the Alzheimer disease cohort, followed by the less pronounced decline in cognition cohort (LCMI, ECMI), and finally the healthy controls. The authors said this shows the model is capable of reproducing the individual multifactorial changes in the brain's accumulation of toxic proteins, neuronal function, and tissue structure seen over time in the clinical scans.

The investigators then used this model to search for genes that result in cognitive decline over time in the healthy aging process, using a subset of healthy control participants who remained clinically stable for nearly 8 years. They found 8 genes that contributed to the imaging dynamics seen in the scans and corresponded with cognitive changes in healthy individuals, according to the results of the study. The genes that changed in healthy aging are also known to affect 2 important proteins in the development of Alzheimer disease, called tau and amyloid beta, according to the study.

They then ran an analysis looking for genes that drive the progression of Alzheimer disease, identifying 111 genes that were linked with the scan data and with associated cognitive changes in Alzheimer disease. Finally, they studied the functions of the 111 genes identified, and found that they belonged to 65 different biological processes, with most of them commonly linked to neurodegeneration and cognitive decline.

Our study provides unprecedented insight into the multiscale interactions among aging and Alzheimer's disease-associated biological factors and the possible mechanistic roles of the identified genes, said Yasser Iturria-Medina, assistant professor at the Department of Neurology and Neurosurgery at McGill University, in the release. We've shown that Alzheimer's disease and healthy aging share complex biological mechanisms, even though Alzheimer's disease is a separate entity with considerably more altered molecular and macroscopic pathways. This personalized model offers novel insights into the multiscale alterations in the elderly brain, with important implications for identifying targets for future treatments for Alzheimer's disease progression.

REFERENCE

Scientists map gene changes underlying brain and cognitive decline in aging [news release]. EurekAlert; May 18, 2021. Accessed May 19, 2021. https://www.eurekalert.org/pub_releases/2021-05/e-smg051821.php

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Mathematical Model of the Brain May Identify Gene Changes Responsible for Cognitive Decline in Aging - Pharmacy Times

What’s the Difference Between Normal Forgetfulness and Signs of Alzheimer’s? – Sarasota

Posted: at 1:57 am


The Brain Health Initiativein Lakewood Ranch held an event on Tuesday, May 18, to honor its Brain Health Scholars Program, which involves more than 60 local high school students who volunteered their time with the initiative over the last year. Each scholar learned to keep their brains sharp and healthy when moving on to college and a career. The keynote speaker was Dr. Lisa Genova, a Harvard graduate, neuroscientist and New York Times bestseller, with books like Still Alice, which was adapted into an Oscar-winning film.

Genova's recent book, Remember, explains to readers how forgetfulness is a normal part of life. She details how factors like sleep, stress and emotion and context can impair memory formation, storage and retrieval. In her talk, she explains the three differences between normal forgetfulness and the early warning signs of Alzheimer's disease.

"There are three kinds of forgetting that are totally normal whether you are 20 or 80 years old," says Genova. These are:

This can refer to when you misplace items easily and instantly blame your memory. Genova says 99 percent of the time, you didn't forget anything. You are just distracted. You weren't paying attention to where you set down your glasses, keys, etc. in the first place. "Paying attention is the first necessary ingredient in creating memory," says Genova. "It is going to last longer than in the present moment. You cannot remember later what you don't pay attention to now."

Genova says this happens to all of us. Proper nouns are more difficult for our brains to remember than common nouns. This has to do with the neuro-connectors involved in remembering these things. "When the name feels like it's on the tip of your tongue, there's another reason why you get to it," says Genova. "Along the way, you come up with loosely related words, therefore focusing on the wrong target." This is a byproduct of how our brains are organized, and there is no harm in Googling the answer.

You may think your memory is failing you, but it's normal. This experience has to do with perspective memory, or what you plan to do later. "These memories are really tough for human brains unless the right cues are available at the right place and time," says Genova. "Outsource this job by making to-do lists or writing everything down. Unless the habit is already engrained in your brain, you are going to forget it." If you forget why you are in a room, go back to the previous room in your house and look around for context clues. You'll most likely remember what you were searching for in the first place.

Genova also explain what Alzheimer's symptoms would look like in these scenarios:

If you lose your car the in parking lot, find it, but don't remember how you got there, it could be cause for concern. Or, if you're standing in front of your car and don't recognize it, or don't remember how to use it. If you've misplaced your phone, keys, etc. and once you've found them, forget how to use them or what they are for, this can be an early sign of Alzheimer's.

Keep in mind that lapses in memory could also be related to other health issues like lack of sleep or B12 deficiency.

What are the things we can consider when keeping our brains healthy and fighting the risk of Alzheimer's disease?

"If you are frequently feeling foggy with respect to memory and forgetting things out of the ordinary, take a look at your sleep patterns," says Genova. Chronically sleep- deprived people will experience what's like amnesia and dementia. We are biologically busy when asleep, so we need 7-9 hours, in order for our hippocampus, or the place that stores memories, to fully consolidate the memory information.

The frontal lobe will also have a hard time paying attention and retaining information the day after a poor night's sleep. When you are sleeping, cells in the brain called glial cells, or janitors of the brain, clear away any metabolic debris and amyloid plaque buildup. Genova says when this buildup reaches a tipping point, around 15-20 years of accumulation, that creates a runaway train that is Alzheimer's. Getting enough sleep will help prevent this.

Caffeine is actually really good for the memory. It increases attention throughout the day, thereby boosting memory. But be careful when you are caffeinating, in order to get proper sleep.

A cooler room will make for a better night's sleep.

Alcohol does not aid sleep and can interfere with REM sleep, the portion of deepest, restorative sleep.

Writing down what you are worried about before heading to bed can help clear anxious thoughts that keep us awake at night.

A brisk walk four times a week can be just enough to help reduce the risk of Alzheimer's.

Staying cognitively and socially active are important for keeping the brain stimulated through all phases of life. Learn a new language or explore a part of town you never have before. Talk walks in new areas, or with friends, or pick up a new hobby.

While Alzheimer's is typically a genetic disease, there are ways that you can alter your lifestyle to help prevent the severity and risk of the disease in your life. Making small changes every day, and understanding that a little forgetfulness here and there is normal, is a big part of the process of keeping our brains sharp.

To learn more about the Brain Health Initiative, click here. To find Dr. Lisa Genova's work, click here.

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What's the Difference Between Normal Forgetfulness and Signs of Alzheimer's? - Sarasota

"Coming out of the closet" with Alzheimer’s: Neurologist Dan Gibbs on his surprise diagnosis – Salon

Posted: at 1:57 am


When I think of Alzheimer's, I don't think of somebody like Daniel Gibbs. I think of my mother, who doesn't know what year it is, or that her husband is dead. I think of tragic movie characters in tearjerker films.

Gibbs would like to change that. As a neurologist, he understands the science of the brain. As an early stage Alzheimer's patient, he recognizes there is so much more to the condition than the singular and extreme narrative we may be familiar with.

In "A Tattoo on My Brain," co-written by Teresa H. Baker, Gibbs reveals how a surprise diagnosis changed his life, and how modern Alzheimer's doesn't have to be the confounding"senility" of generations past. With equal parts humility and curiosity, he offers a firsthand account of a disease that affects5.8 million Americans, and for which there is no cure.And he investigates the new thinking and clinical research that's offering hope to patients like him, as well as people like me, who wonder what might lurkin our own genetic future.

Salon spoke to Gibbs recently about the myths of misconceptions of Alzheimer's, and how his sense of smell tipped him off to a bigger problem. As always, this interview has been condensed and edited for clarity.

In your book, you call yourself a "lumper."Whatdoyou want people to understand about Alzheimer's, about dementia,all of those things that we "lump" together?

There's a parallel with cancer because Alzheimer's researchis about thirty or forty years behind our understanding of cancer. Back in the fifties and sixties, cancer was just all thought to be about the same the cells went wrong and grew, and if you could kill one cancer, you might be able to kill them all. Obviously, that wasn't true. Alzheimer'shasbeen following the same path. When I was first in practice, we couldn't do anything about any of the dementias.I lumped them together because it didn't seem to be fruitful to make a distinction between Alzheimer's disease and Lewy body dementia or Parkinson's dementia or vascular dementia, frontotemporal dementia.

When the first drug, Aricept, came outinthe nineties, it became important for me anyway to make a distinction, because Aricept provides some benefits to some people with Alzheimer's, some people Lewy body dementia. But it can make symptoms from frontotemporal dementiaactually worse. It was important to get rid of the shotgun approach and more fine tune.

Just in the last year, in the last few months, we're finding that there are probably subtypes of what we call Alzheimer's that really aren't quite the same thing on a molecular level. They probably will respond or not respond differently to various attempts to reverse the disease or to slow it down.

That's become apparent in the trials of disease modifying medications, like the anti-amyloid monoclonal antibodies, the trial that I was in. Early on the trials of the first drug, showed absolutely no benefit.But in those first trials, they weren't able to test to see if people actually had Alzheimer's disease. That was before the amyloid pet scan was available.Now, all of the trials require a pet scans for amyloids, to show that the people all have these amyloids in their brain. It doesn't mean they have Alzheimer's disease, but it means that they are probably on the path.

My feeling is we're going to have to push the target age earlier, working on treatmentseven before people have cognitive impairment.It's not as simple as one type of cancer;it's probably not one simple type of Alzheimer's disease. We have to understand more about the different subtypes before we figure out how to attack it.

That's crucial, becausea lot of ushave a particular narrative in our heads about what it looks like when someone has Alzheimer's.Anthony HopkinsandJulianne Moore have won Oscars for it.Yet you start your story with very different symptoms,that we don't necessarily recognizeas being part of Alzheimer's.

I started to lose my sense of smell at least fifteen years ago, and didn't think anything of it because everybody, as they get older has a decrease in their sense of smell. But about a year into it, I started to haveweird, illusory odors, which incidentally are not the characteristics of Alzheimer's disease. That there's nothing in the literature that I could find that showed an association.

Butthat got my attention because that wasweird to have these smells come out of nowhere that werea cross between baking bread and perfume, that would last a few minutes or maybe an hour. I wasmore interested to see if I might be at risk forParkinson's disease, because olfactory disorders are much better recognized in Parkinson's. Alzheimer's wasn't on my radar screen at all.

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There are psychological symptoms that maybe someone who is looking atchanges in their own behavior ormental state may not realize might be symptomatic. What was that like for you?

Apathy is so common.I think it's probably due to one of the first parts of the brain that starts to accumulate amyloid is the prefrontal cortex. That's the part of the brain right in the front that is involved in motivation. It's where we come up with plans for doing things. It just makes sense to me. That probably is the structural correlateof why we get apathy.I certainly havea hard time doing stuff. I'm content with the isolation of COVID and don't really have a particular interest in going out again now that I can goto the theater or something like that. I have to push myself to do that, or my wife has to push me.

That's very common and it's often very early. The thingslike the paranoia,the real psychiatric symptoms that can be so difficult for everybody, are usually later.Unfortunately I think what we've all considered to be Alzheimer's disease is that late stage. When I was practicing neurology, at least in the firstten or fifteen years, that was the first time I saw somebody with Alzheimer's. They wouldn't come to the doctor until those late stages, and there wasn't really anything to do back then. There still isn't much to do. And there probably won't be much to do for those people in terms of trying to reverse the process, because by that time brain cells are dead and we just don't have a clue how to bring them back.

The first successes in terms of disease modification, in my opinion, are going to be in the earliest stages of the disease, but probably before people have any symptoms and that's going to be really hard to manage.

Over the past year or soit has been harder for all of us to really assess our own mental and physical health,andthat of our loved ones.Do you feel that this pandemic has had a detrimental effect on people who are vulnerable to Alzheimer's and people living with Alzheimer's?

I don't think that I can say that it's had a detrimental effect on me per se, but I think people who are living by themselves, it must be terrible if they have early Alzheimer'sto have that additional isolation. We have four grandchildren, and for the last couple of months, we've been able to get together.I think the isolation has been really hard for the people who aren't able to interact in person with anybody.

For those of us who are in the caregiver roles or extended family member roles,who see this in our families, it's scary. What do you tell those of us who are either facing this diagnosis or worry that we're going to face it?

It's so important that we're able to come out of the closet with Alzheimer's because there's beenthis real stigma attached to it. People are afraid of people withAlzheimer's. They don't know how they interact with them, and there's a drawing back. I see that even from myself. The first reaction that people tend to have when I tell them that I have Alzheimer's, especially a few years ago, was, "Oh, no, of course you don't have Alzheimer's,"because it doesn't fit the paradigm that people have in their mind of the image of what someone with Alzheimer's ought to look like.I make it a point to just lay it out there before people can be put off by it. Everybody in our neighborhood knows I have Alzheimer's,and I think that's good.

The peoplethat might want less to talk about it, are older people,because it's maybe a little more threatening to them. Younger people are more open minded about it.I think that's really great because that's my target audience,especially if they have a family history of Alzheimer's because the biggest risk factor is a parent or a sibling with Alzheimer's. Those are the people who really need to start doing something about it when they're middle age or before. There's really good data that some of these lifestyle modifications that I go into in the book can reduce the risk of getting Alzheimer's when you're in your seventies or eighties. But they have to be started early.

If you wait until you're 70 and starting to have memory issues,the horses are out of the barn to certain extent. I's much more effective to start exercising regularly and eating well and gettingsleep. There was a really good study that came out a few weeks ago that gave us the best data yet about how important it is to have adequate sleep in midlife. And that's the hardest time to get adequate sleep, because we're so busy.They found that that people who got six or less hours of sleep a night had a 30 percent greater risk of getting Alzheimer's than people who got seven or more hours of sleep at night. I go into some of that about sleep in the book about why that might be happening. The glymphatic circulation in the brain.

Tthe bottom line is it really does help, but it needs to be midlife. It doesn't help start trying to get a lot of sleep when you'vealready got Alzheimer's. By that time, it's really hard to get adequate sleep because Alzheimer's stalls up sleep patterns. It's got to be early, and that's going to be the case for the drugs that finally work to slow down or keep us from getting Alzheimer's. I think they're going to have to be used in people in their fifties, before they have any signs of disease, but that's a bit of a controversial assertion.

How do you feel about early genetictesting and testing if you don't have symptoms?

A reason to get tested would be, if you had a family history,and if you're interested in getting involved in a study. We're going to need thousands of people in that category,to have an impact on preclinical disease.I don't recommend that people go out and get tested for Alzheimer's without any structure. I think if you want to get tested that's okay, butit should be done under supervision so that somebody can explain what your risk really is.

That's going to get even more complicated within a few years, because I think we're just a few years from having really good blood tests for both amyloid and tau available that will really prove the diagnosis of pre symptomatic Alzheimer's disease.

If have a first degree relative without Alzheimer's, so then you ought tobe out there getting 10,000 steps or running, getting your aerobic exercise every day, or at least three times a week at the very least. A lot of people don't enjoy or think don't think they enjoy the heart and brain healthy diets that are more plant-based, but that would be a good thing to at least make an effort to head towards. It's good for your heart, it's good for your blood pressure,it reduces risk of diabetes and it's good for your brain. I would recommend at least those modifications and trying to get some sleep and staying intellectually active. You don't have to know whether you've got the gene for it, or whether you've got tau or amyloid in your brain. At least for right now, just for those who have a family history, I would really recommend making the lifestyle modifications. It doesn't matter whether or not you know that you have a genetically disposition or already having amyloid.

I was thinking recently how much my fear of cancer has changed because of my dad dying at 60, whenI was only 16. I've always been worried that I was going to have cancer.I was really dreading it. Now that I have Alzheimer's,my view of cancer is totally changed and I'm not afraid of cancer anymore.I'm hopingthat the things I'm doing in my life to mitigate the effects of Alzheimer's will prolong my life, prolong my healthy brain part of life, for as long as it takes for something else to kill me. Because I don't want to die of Alzheimer's disease.

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"Coming out of the closet" with Alzheimer's: Neurologist Dan Gibbs on his surprise diagnosis - Salon

Jeri Fields: Faster processing of disability claims for people with Alzheimer’s Disease – The Tribune | The Tribune – Ironton Tribune

Posted: at 1:57 am


Today, more than 5 million Americans are living with Alzheimers disease. Since the onset of Alzheimers can occur in people before they retire, it may strike during an individuals working years; preventing gainful employment as the disease progresses.

As a result, people must come to grips with a devastating diagnosis while losing their salary and benefits. People with Alzheimers disease and their caregivers must figure out how theyll pay for care. Our benefits and services are vital to people with early-onset Alzheimers who are unable to work and have no other source of income.

For over a decade, Social Security has included Alzheimers disease in our Compassionate Allowances program. The Compassionate Allowances program identifies debilitating diseases and medical conditions so severe they obviously meet our disability standards. Compassionate Allowances allow for faster processing of disability claims for individuals with Alzheimers disease, mixed-dementia, and Primary Progressive Aphasia.

You can read more about our Compassionate Allowances program at http://www.ssa.gov/compassionateallowances. To learn more about how Social Security disability insurance works, visit our disability page at http://www.ssa.gov/disability. Please share these resources with friends and family.

Jeri Fields is the manager of the district Social Security office in Ironton.

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Global Dementia and Alzheimer’s Disease Treatment Market Analysis on Industry Trends, Drivers, Application and Segmentation 2020 to 2025 The Manomet…

Posted: at 1:57 am


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Senior Ifeoma Ezeilo attributes success to family, EOP and hard work | Binghamton News – Binghamton University

Posted: at 1:56 am


After losing her father to a heart attack when she was just eight years old, Ifeoma Ezeilo decided to turn her pain into a passion for helping others. This passion has fueled all four years of her time at Binghamton University and will continue to motivate her throughout her next chapter of life medical school.

Ezeilo, known as Ify by her friends, is a senior majoring in Africana studies and minoring in chemistry. She was born in Brooklyn, N.Y., but her parents immigrated to the United States from Nigeria. She has four siblings, and after her older sister was accepted to Binghamton University through the Educational Opportunity Program (EOP), Ezeilo was inspired to follow in her footsteps.

Her time at Binghamton is marked by extensive academic accomplishments and leadership positions, including maintaining the highest grade-point average among her peers in EOP every semester. In addition to her regular schoolwork, Ezeilo was often in the research lab examining nanoparticles reaction to gold. Its hoped that this research might lead to ways to help detect diseases earlier. She is also a resident assistant in Hinman College, the senior advisor of the Charles Drew Minority Pre-Health Society and an emergency medical technician with Harpurs Ferry.

In addition to all of this, she is currently writing her honors thesis, in which she explores the skin bleaching of immigrants from West Africa. More specifically, she is delving into the psychological effects of skin bleaching by interviewing people who were exposed to the concept and people who have actually bleached their skin. This research recently earned her the Provosts Award for Excellence in Undergraduate Research.

Ezeilo attributes her college success to many people, including her EOP tutor, Jada McMahon, and her family.

Ezeilo said that McMahon worked with her for hours each week supporting not only her schoolwork, but her mental health. McMahon had faith in her even when she did not have faith in herself, she said, and constantly pushed her to persist through the difficulties of pre-med schoolwork. And when she had been in the tutoring center for too long, McMahon often took her on walks in the fresh air to clear her mind.

Ezeilos family has been a constant source of support as well. Her sister also lived in Hinman and offered her guidance whenever she needed it, and her mother was always a phone call away to talk with and pray with. Even her father is still a motivating force in her life. His early death led to her dreams of pursuing a medical career.

I remember telling my mom that I wanted to be a cardiologist after [his death], she said. I told her that I wanted to prevent what happened to dad from happening to other people. She has since decided not to be a cardiologist, but plans to practice family medicine. She was recently accepted into several medical schools and is currently mulling over her choices for where she will attend. Her goal is to find a happy medium between allopathic and holistic medicines, and her ultimate dream is to open a clinic in Nigeria, where she knows there is a great need for hospitals that are in closer proximity to the rural villages than currently exist.

Despite all of Ezeilos achievements, she is clear that college has not been easy, courses are difficult and she has put in a lot of time and hard work to achieve what she has. Every single year I get a 4.0, and people think its just because Im naturally smart, she said, but it doesnt come easily. It comes with breakdowns and pep talks with my sister, strategizing about my next test with [McMahon] and talking to my mom as an outlet and praying together.

She said that sometimes she has been viewed by her peers merely as a calculator or an extra teacher for a course from whom they hoped to get the answers. Ezeilo also battled with comparing herself and her intelligence to others in her classes and being unable to celebrate her accomplishments without thinking about how to accomplish her next goal.

Now, as her senior year is ending and this chapter of her life is coming to a close, Ezeilo said that she can finally celebrate herself and her accomplishments. I ended up achieving the highest GPA every semester since freshman year, she said. Its a nice accomplishment and something that I am now coming to terms with being proud of and celebrating. I have never stopped to think, Wow, Ify, you did that. Other people would always tell me that, and now when I look back at my years in undergrad and in EOP I can finally say, Yeah. Yeah, I did do that.

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