About Us

Archives






[Development of an adenovirus vector containing a hepatitis C virus expression cassette and its application].

Posted: May 26, 2013 at 2:55 am


Authors: Yoshida T, Kondoh M, Mizuguchi H, Yagi K
Abstract
Hepatitis C virus (HCV) is a hepatotropic member of the Flaviviridae family and contains a 9.6 kb positive-sense RNA genome. Approximately 170-million people are infected with HCV worldwide. These people face increased risks of chronic hepatitis, cirrhosis and hepatocellular carcinoma compared with the general population. Transduction of the HCV genome into hepatocytes is essential for understanding the mode of action of HCV infection, and for preparing HCV, evaluating HCV replication, and screening anti-HCV drugs. Although electroporation of in vitro-synthesized HCV genome and transduction of plasmid vectors containing the HCV genome are widely used in HCV research, a more convenient system with higher transduction efficie...

MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Source:
http://www.medworm.com/index.php?rid=7281310&cid=c_449_13_f&fid=36240&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F23449406%3Fdopt%3DAbstract

Related Post

No Comments

No comments yet.

Sorry, the comment form is closed at this time.